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5 L 316L Stainless Steel Fermenter Bioreactor

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316L Stainless Steel Fermenters

SJ-FS-DJ-5L — 5 L total volume; 1.5-3.5 L planning working range. Small-volume microbial screening, media development and training. A double-wall water jacket, 10-inch MCGS touchscreen, PLC control, pH / DO monitoring and four liquid-addition channels provide an integrated platform for microbial process development.

5 L 316L Stainless Steel Fermenter Bioreactor concept illustration
Concept illustration; final supplied configuration follows the approved quotation and drawings.

Why choose a 316L stainless steel fermenter?

A 316L product-contact vessel provides a metal construction for repeated laboratory development campaigns. The separate thermal jacket supports heating and cooling around the culture. Surface finish, cleaning access, seals and drainability are specified for the application. The proposed manual SIP package requires an agreed vessel pressure design, steam utility, valves and drainage; automated SIP is an option.

Functions and customer benefits

Function / featureWhat it doesBenefit to your workflow
10-inch touchscreen + PLCCentralizes process values, settings and operating commands.Check the process from one interface and organize routine operation.
Water-jacket temperature controlCirculates a heating/cooling medium around the culture vessel.Adjust culture temperature without a cooling coil occupying culture space.
Variable-speed agitationAdjusts stirring within the selected drive and impeller range.Tune mixing to culture volume, viscosity and oxygen-transfer needs.
pH monitoring and dosingMeasures pH and uses acid/base pump channels under agreed control logic.Correct pH changes with less repeated manual addition.
Dissolved oxygen monitoringMeasures oxygen availability; agitation response is configured to the process.Identify oxygen limitation and guide the control strategy.
Four peristaltic pumpsProvides acid, base, nutrient feed and antifoam channels.Keeps addition duties separate and supports planned feeding.
Foam contact detectionDetects foam at a chosen height and triggers limited antifoam pulses.Respond to foam without relying only on visual checks.
Air / oxygen gas channelsIndicates flow through manually adjusted rotameters.Set the gas supply for each trial; automatic flow requires an MFC upgrade.
Exhaust condenserCondenses part of the moisture in outgoing gas.Helps reduce evaporation and moisture carry-over; sterile filtration is separate.
Rear-access sheet-metal cabinetPlaces cabinet fasteners at the rear with clean front and side panels.Provides an uncluttered operator-facing surface and an organized service layout.

Optional automation and project upgrades

Multi-stage recipes can define temperature, pH, DO, agitation limits, feeding and stage-transition conditions. Automatic gas-flow / oxygen cascade requires the agreed MFC package. Data export, access roles, SCADA and qualification documentation are specified separately in the quotation. These options are not included automatically.

Applications in biotechnology and pharmaceutical research

Designed for laboratory microbial fermentation: bacterial and yeast culture, media optimization, enzyme production research, probiotic process development, recombinant microbial expression and training. Batch and fed-batch workflows are configured to the organism, feeding strategy and oxygen demand.

For pharmaceutical process development, send the URS and required documentation scope. Mammalian cell culture, high-viscosity broths and unusual solvents require a separate engineering review; a standard microbial package is not automatically suitable for every process.

Configuration and technical parameters

ParameterProposed configuration
Vessel / wetted material316L product-contact vessel with separate stainless-steel thermal jacket
Total / working volume5 L / 1.5-3.5 L (planning range)
HMI10-inch MCGS touchscreen
PLCXinje PLC base proposal; Siemens SMART G2 option, exact CPU and I/O subject to engineering
Agitation50-1000 rpm proposed, impeller and torque dependent
Culture temperatureProposed culture operating range: cooling-water temperature +5 C to 60 C; heat-load dependent
pH measurement2-12 proposed measurement range; sterilizable domestic probe
Dissolved oxygen measurement0-200% air saturation proposed measurement range; sterilizable domestic probe
Liquid addition4 peristaltic pumps: acid, base, nutrient feed and antifoam
Gas channels2 manual rotameter channels: air and oxygen; oxygen-ready gas train, MFC upgrade optional
Foam controlAdjustable conductive probe plus isolated foam detector; PLC pulse-doses antifoam
Thermal systemWater-jacket circulation with electric heater, circulation pump and cooling-water control; external chiller optional
SterilizationManual SIP engineering package proposed, requiring agreed pressure design and steam utility; automated SIP optional
Culture pressurePressure design and operating limit to be specified on approved vessel drawing; no generic rating claimed
CabinetFolded sheet-metal cabinet and base; rear cabinet fasteners; screw-free front and side panels
OriginZhejiang, China
External utilitiesChiller, compressor, oxygen supply, autoclave / steam generator are quoted separately when required
Packing / shippingPacking dimensions and gross weight confirmed after approved mechanical design and crating; request the final packing list

Measurement ranges are not control-accuracy guarantees. Performance, utility requirements and acceptance tests follow the approved technical specification and FAT checklist. Images are concept illustrations, not photographs of a measured production unit.

Explore the equipment and controls

5 L 316L Stainless Steel Fermenter Bioreactor configuration concept 2
Concept illustration; final supplied configuration follows the approved quotation and drawings.
5 L 316L Stainless Steel Fermenter Bioreactor configuration concept 3
Concept illustration; final supplied configuration follows the approved quotation and drawings.
5 L 316L Stainless Steel Fermenter Bioreactor configuration concept 4
Concept illustration; final supplied configuration follows the approved quotation and drawings.

5 L, 10 L and 15 L model comparison

Model / materialTotal volumeWorking range*
SJ-FG-DJ-5L
Borosilicate glass
5 L1.5-3.5 L
SJ-FG-DJ-10L
Borosilicate glass
10 L3-7 L
SJ-FG-DJ-15L
Borosilicate glass
15 L4.5-10.5 L
SJ-FS-DJ-5L
316L stainless steel
5 L1.5-3.5 L
SJ-FS-DJ-10L
316L stainless steel
10 L3-7 L
SJ-FS-DJ-15L
316L stainless steel
15 L4.5-10.5 L

*Planning working ranges depend on mixing, aeration, foam and the organism. Model capacity refers to total vessel volume.

Made to order in Zhejiang, China. Request a quotation matched to your selected configuration, utilities and documentation needs. External utilities and optional upgrades are supplied only when specified. Planning lead time: 60 calendar days after technical and commercial approval; confirm before ordering. Proposed warranty: 12 months for manufacturing defects, subject to quotation terms.

Frequently asked questions

Does 10 L mean 10 L of culture?

No. Capacity identifies total vessel volume. The planning working ranges are 1.5-3.5 L, 3-7 L and 4.5-10.5 L for the 5 L, 10 L and 15 L models.

How is heat removed?

Cooling water circulates through the jacket. An external chiller may be needed when available water is too warm or the culture heat load is high.

What does the exhaust condenser do?

It helps condense moisture in the exhaust and reduce evaporation and carry-over. It does not replace the sterile exhaust filter.

Does the foam probe measure foam percentage?

No. The conductive probe detects contact at a chosen height. The PLC can apply limited antifoam pulses; this is a point-detection system.

Are all stainless models automatically SIP-ready?

No. Sterilization depends on the agreed vessel, pressure design, seals, valves, steam conditions and drainage. Automated SIP is a separate option.

Can the glass vessel be steam-sterilized in place?

Do not assume this. The proposed glass route is off-line autoclaving of approved components within their permitted cycle and pressure/temperature limits.

Are chiller, compressor and sterilizer included?

Only if separately listed in the quotation. The base equipment and external utilities are itemized so the quotation matches your site.

Can you support pharmaceutical or biotech projects?

Send your URS, organism and documentation needs. Qualification support and data-integrity functions are agreed separately; no blanket GMP or electronic-record compliance is claimed.

Information to include in your enquiry

Tell us the organism, total and working volume, batch or fed-batch process, broth viscosity, target temperature, aeration / oxygen demand, sterilization route, utilities, electrical supply, recipe and data requirements, delivery address and documentation scope. This lets us match the vessel, drive, probes, gas train and software to your process.

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